RhoG Promotes Neural Progenitor Cell Proliferation in Mouse Cerebral Cortex

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RhoG promotes neural progenitor cell proliferation in mouse cerebral cortex.

In early cortical development, neural progenitor cells (NPCs) expand their population in the ventricular zone (VZ), and produce neurons. Although a series of studies have revealed the process of neurogenesis, the molecular mechanisms regulating NPC proliferation are still largely unknown. Here we found that RhoG, a member of Rho family GTPases, was expressed in the VZ at early stages of cortica...

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ژورنال

عنوان ژورنال: Molecular Biology of the Cell

سال: 2009

ISSN: 1059-1524,1939-4586

DOI: 10.1091/mbc.e09-03-0200